Traffic accidents are the leading cause of death and severe injuries worldwide. Iran, as a low-to-middle-income country, accounts for a significant portion of traffic accidents. As a result, providing a comprehensive overview and analysis of traffic accidents and emergency response performance across Iran is a crucial step in identifying critical trends and patterns to enhance road safety and accident management. In this research, three datasets, including traffic police data, Forensic Medicine Organization data, and Red Crescent's rescue operation data, between 2016 and 2023, were analyzed. The analysis of traffic police data revealed that the most frequent accident types were vehicle collisions with pedestrians and motorcyclists. However, accident types such as rollovers and run-off-road accidents, despite their lower frequency, accounted for a higher proportion of deaths as a result of their higher severity. Additionally, the analysis of data from the Forensic Medicine Organization demonstrated that nearly half of the deaths occurred at the crash scene, and passenger vehicle drivers, motorcyclists, and pedestrians accounted for a significant portion of the deaths. Provinces such as Tehran, Alborz, Mazandaran, and Razavi Khorasan showed high rates of pedestrian deaths, while Bushehr, Qom, and Yazd had high rates of motorcyclist deaths. The analysis of Red Crescent rescue operations revealed a decrease in the proportion of injured people who received assistance in recent years. In addition, the reporting time for accidents to the Red Crescent exceeded 10 minutes in almost 11% of cases, and the arrival time of rescue teams at accident sites took longer than 20 minutes in 12.5% of cases. Furthermore, significant differences were observed in response times between provinces, indicating the need for region-specific analysis, strategies, and planning.